Data/hora: 07/06/2024 02:19:44

Provedor de dados: | 52
País: | Brazil
Título: | Isolation of new steroids of Kala Dhaman grass (Cenchrus setigerus) and evaluation of their bioactivity
Autores: | Singariya,Premlata; Kumar,Padma; Mourya,Krishan Kumar.
Data: | 2014-02-01
Ano: | 2014
Palavras-chave: | Cenchrus grass; Photosynthetic pigments; Total soluble sugar; Proline; Antibacterial activity; MIC; MBC/MFC.
Resumo: | The present study was carried out to determine the possible bioactive components (steroids) of Cenchrus setigerus using GC-MS analysis and in vivo estimation of metabolites (total soluble sugar, soluble protein, proline and total phenolics), photosynthetic pigments (chlorophyll-a, chlorophyll-b and carotenoids) of seedlings and antimicrobial activity of extracts in various polar solvents from the leaves of C. setigerus. Antimicrobial activity was evaluated against three Gram-negative bacteria, including Proteusmirabilis, Klebsiella pneumonia and Agrobacterium tumefaciens andone fungus Aspergillus niger using 'disc diffusion' method, followed by the determination of minimum inhibitory concentrations (MIC) by broth dilution method. Results revealed the presence of some steroids in the isopropyl alcohol extract of C. setigerus:which are (22E)-stigmasta-4,22-dien-3-one(4.93%), δ4-sitosterol-3-one (stigmast-4-en-3-one) (4.31%), fagarsterol (lupeol) (1.25%) and ethyl iso-allocholate (0.32%). Total soluble sugars and chlorophyll-a were also recorded to be highest. The highest activity was exhibited by the isopropyl alcohol and ethyl acetate extract against P. mirabilis.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132014000100010
Editor: | Instituto de Tecnologia do Paraná - Tecpar
Relação: | 10.1590/S1516-89132014000100010
Formato: | text/html
Fonte: | Brazilian Archives of Biology and Technology  v.57 n.1 2014
Fonte: | info:eu-repo/semantics/openAccess