Data/hora: 10/06/2024 13:52:59

Provedor de dados: | 52
País: | Brazil
Título: | Effect of an extract of Artemisia vulgaris L. (Mugwort) on the in vitro labeling of red blood cells and plasma proteins with technetium-99m
Autores: | Terra,Danielle Amorim; Amorim,Lúcia de Fátima; Catanho,Maria Tereza Jansen de Almeida; Fonseca,Adenilson de Souza da; Santos-Filho,Sebastião David; Brandão-Neto,José; Medeiros,Aldo da Cunha; Bernardo-Filho,Mario.
Data: | 2007-09-01
Ano: | 2007
Palavras-chave: | Artemisia vulgaris L.; Technetium-99m; Blood constituents; Labeling.
Resumo: | The aim of this work was to evaluate the effect of an extract of the Artemisia vulgaris L. (mugwort) on the labeling of blood constituents with technetium-99m (99mTc). Blood samples from Wistar rats were incubated with a mugwort extract and the radiolabeling of blood constituents was carried out. Plasma and blood cells were separated by centrifugation. Aliquots of plasma and blood cells were also precipitated with trichloroacetic acid and centrifuged to isolate soluble and insoluble fractions of plasma and blood cells. Radioactivity in each fraction was counted and the percentages of radioactivity (%ATI) was calculated. Mugwort extract decreased significantly (p&lt;0.05) the %ATI on the blood compartments and on the blood cells proteins (insoluble fraction). The analysis of the results indicates that the extract could have substances that could interfere on the transport of stannous through the erythrocyte membrane alterating the labeling of blood cells with 99mTc.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132007000600015
Editor: | Instituto de Tecnologia do Paraná - Tecpar
Relação: | 10.1590/S1516-89132007000600015
Formato: | text/html
Fonte: | Brazilian Archives of Biology and Technology  v.50 n.spe 2007
Fonte: | info:eu-repo/semantics/openAccess