Data/hora: 10/06/2024 17:35:38

Provedor de dados: | 52
País: | Brazil
Título: | Alveolus-capillary permeability on both normal and HIV seroreactive individuals
Autores: | Carriel,José Carlos; Maliska,Carmelindo; Piloto,José Henrique; Norberg,Antônio Neres; D’Almeida,Joaquim; Ferreira,Gilsy S.; Penas,Maria Expósito.
Data: | 2007-11-01
Ano: | 2007
Palavras-chave: | HIV seroreactive; Alveolus-capillary permeability; 99mTc-DTPA clearance; Pneumocystis pneumonia.
Resumo: | The aim of this study was to evaluate the alveolus-capillary permeability by the lung clearance rate of 99mTc-DTPA(Technetium99m-diethylene triamine penta-acetate), (LCR-DTPA), both in normal and in asymptomatic HIV seroreactive patients. Thirty individuals were studied, 21 seronegative normal volunteers and 9 HIV seroreactive patients presenting normal chest radiography and no respiratory infection symptoms. LCR-DTPA was determined by inhaling 99mTc-DTPA and obtaining images in a gamma camera. The 99mTc-DTPA clearance rate in normal individuals was 0.99±0.15%.min-1 and in patients 2.31±1.25%.min-1. There was a significant statistical difference between the two groups (p&lt; 0.05). Two patients who presented LCR-DTPA higher than 4.3 %.min-1 presented pneumocystis pneumonia one month later. Seroreactive AIDS patients, previously asymptomatic that presented pneumonia later showed higher LCR-DTPA than the seroreactive who did not develop the illness. These results suggested that LCR-DTPA could be a predictive method for the clinical development of pneumocystis pneumonia in asymptomatic HIV seroreactive patients.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132007000700008
Editor: | Instituto de Tecnologia do Paraná - Tecpar
Relação: | 10.1590/S1516-89132007000700008
Formato: | text/html
Fonte: | Brazilian Archives of Biology and Technology  v.50 n.6 2007
Fonte: | info:eu-repo/semantics/openAccess