Data/hora: 02/06/2024 07:08:27

Provedor de dados: | 55
País: | Brazil
Título: | An open label, multicenter, non-comparative study of the efficacy and safety of oral gatifloxacin in the treatment of community-acquired pneumonia: a Brazilian study in five centers
Autores: | Nicodemo,Antonio Carlos.
Data: | 2003-02-01
Ano: | 2003
Palavras-chave: | Gatifloxacin; Community-acquired pneumonia; Brazil.
Resumo: | We made an open label, multicenter, non-comparative study to assess the efficacy and safety of oral gatifloxacin, 400mg PO given once-daily during 7 to 14 days for the treatment of adult outpatients with community-acquired pneumonia at five Brazilian medical facilities. Among the 86 subjects available for clinical evaluation, 84 (98%) were cured. The bacteriological eradication and presumed eradication rate was 98% (52/53) among the 44 (51%) patients who were bacteriologically evaluated. Drug-related adverse events were reported by 27% of the patients, diarrhea being the most frequent, occurring in 12% of patients. Adverse events were considered mild (89%) or moderate (11%). We conclude that a 7-14 day course of gatifloxacin, 400mg PO given once daily is safe and effective for the treatment of community-acquired pneumonia. The drug had a favorable safety profile and a good clinical and bacteriological efficacy.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702003000100007
Editor: | Brazilian Society of Infectious Diseases
Relação: | 10.1590/S1413-86702003000100007
Formato: | text/html
Fonte: | Brazilian Journal of Infectious Diseases  v.7 n.1 2003
Fonte: | info:eu-repo/semantics/openAccess