Data/hora: 04/06/2024 04:36:54

Provedor de dados: | 55
País: | Brazil
Título: | Risk factors of oropharyngeal carriage of Pseudomonas aeruginosa among patients from a Medical-Surgical Intensive Care Unit
Autores: | Fortaleza,Carlos Magno Castelo Branco; Figueiredo,Lígia Castellon; Beraldo,Carolina Contador; Melo,Edson Carvalho de; Póla,Patrícia Maria Sales; Aragão,Valéria Drummond Nagem.
Data: | 2009-06-01
Ano: | 2009
Palavras-chave: | Pseudomonas aeruginosa; Colonization; Oropharyngeal carriage; Surveillance cultures; Intensive care unit.
Resumo: | Oropharyngeal carriage of Pseudomonas aeruginosa is associated with increased risk of infection and may provide a source for spread of drug-resistant strains. In order to assess the incidence and risk factors of oropharyngeal carriage, we conducted a retrospective cohort study based on results of surveillance cultures (oropharyngeal swabs) from a medical-surgical intensive care unit, collected from March 2005 through May 2006. Variables investigated included demographic characteristics, comorbid conditions, invasive procedures, use of devices and use of antimicrobials. Thirty case patients with P. aeruginosa carriage were identified. Other 84 patients with surveillance cultures negative to P. aeruginosa were enrolled as control subjects. Case patients were more likely to have a solid malignancy (Odds Ratio [OR] = 12.04, 95% Confidence Interval [CI] = 1.93-75.09, p=0.008), Acquired Immunodeficiency Syndrome (AIDS, OR = 7.09, 95% CI= 1.11-45.39, p = 0.04), central nervous system disease (OR = 4.51, 95% CI = 1.52-13.39, p = 0.007), or to have a central venous catheter placed (OR = 7.76, 95% CI = 1.68-35.79, p=0.009). The use of quinolones was a protective factor (OR = 0.13, 95% CI = 0.03-0.47, p = 0.002). The predominance of comorbidities as risk factors points out a group of patients to whom preventive measures should be directed.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702009000300004
Editor: | Brazilian Society of Infectious Diseases
Relação: | 10.1590/S1413-86702009000300004
Formato: | text/html
Fonte: | Brazilian Journal of Infectious Diseases  v.13 n.3 2009
Fonte: | info:eu-repo/semantics/openAccess