Data/hora: 03/06/2024 16:55:20

Provedor de dados: 	55	
País: 	Brazil	
Título: 	Clinical presentation of leptospirosis: a retrospective study of 201 patients in a metropolitan city of Brazil	
Autores: 	Daher,Elizabeth F; Lima,Rafael SA; Silva Júnior,Geraldo B; Silva,Eveline C; Karbage,Nahme NN; Kataoka,Raquel S; Carvalho Júnior,Paulo C; Magalhães,Max M; Mota,Rosa MS; Libório,Alexandre B.	
Data: 	2010-02-01	
Ano: 	2010	
Palavras-chave: 	Leptospirosis; Clinical manifestations; Laboratory findings; Mortality.	
Resumo: 	INTRODUCTION: leptospirosis is a zoonosis of worldwide importance. The disease is endemic in Brazil. This study was conducted to describe the clinical and laboratory presentation of leptospirosis in a metropolitan city of Brazil. METHODS: this is a retrospective study including 201 consecutive patients with leptospirosis admitted to tertiary hospitals in Fortaleza, Brazil, between 1985 and 2006. All patients had clinical and epidemiological data suggestive of leptospirosis, and positive laboratorial test for leptospirosis (microscopic agglutination test, MAT, higher than 1:800). RESULTS: a total of 201 patients were included, with mean age of 38.9 ± 15.7 years; 79.1% were male. The mean length from onset of symptoms to admission was 7 ± 3 days. The main clinical signs and symptoms at admission were fever (96.5%), jaundice (94.5%), myalgia (92.5%), headache (74.6%), vomiting (71.6%) and dehydration (63.5%). Hemorrhagic manifestations were present in 35.8%. Acute kidney injury was found in 87% of the patients. Platelet count was less than 100,000/mm³ in 74.3%. Hematuria was found in 42.9%. Death occurred in 31 cases (15.4%). CONCLUSIONS: leptospirosis is a globally relevant disease with potential fatal outcome. Signs and symptoms suggestive of leptospirosis must be known by any physician in order to institute early adequate treatment to improve outcome. Early indication and daily hemodialysis seems to be beneficial in this group of patients.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000100002	
Editor: 	Brazilian Society of Infectious Diseases	
Relação: 	10.1590/S1413-86702010000100002	
Formato: 	text/html	
Fonte: 	Brazilian Journal of Infectious Diseases  v.14 n.1 2010	
Fonte: 	info:eu-repo/semantics/openAccess