Data/hora: 03/06/2024 03:32:52

Provedor de dados: | Brazilian Journal of Infectious Diseases
País: | Brazil
Título: | Elevated serum CA 19-9 levels in patients with pulmonary nontuberculous mycobacterial disease
Autores: | Hong,Ji Young; Jang,Sun Hee; Kim,Song Yee; Chung,Kyung Soo; Song,Joo Han; Park,Moo Suk; Kim,Young Sam; Kim,Se Kyu; Chang,Joon; Kang,Young Ae.
Data: | 2016-02-01
Ano: | 2016
Palavras-chave: | Carbohydrate antigen 19-9; Nontuberculous mycobacteria; Tuberculosis; Biological marker.
Resumo: | Abstract Increased serum CA 19-9 levels in patients with nonmalignant diseases have been investigated in previous reports. This study evaluates the clinical significance of serum CA 19-9 elevation in pulmonary nontuberculous mycobacterial disease and pulmonary tuberculosis. The median CA 19-9 level was higher in patients with pulmonary nontuberculous mycobacterial disease than in patients with pulmonary tuberculosis (pulmonary nontuberculous mycobacterial disease: 13.80, tuberculosis: 5.85, p &lt; 0.001). A multivariate logistic regression analysis performed in this study showed that Mycobacterium abscessus (OR 9.97, 95% CI: 1.58, 62.80; p = 0.014) and active phase of pulmonary nontuberculous mycobacterial disease (OR 12.18, 95% CI: 1.07, 138.36, p = 0.044) were found to be risk factors for serum CA 19-9 elevation in pulmonary nontuberculous mycobacterial disease. The serum CA 19-9 levels showed a tendency to decrease during successful treatment of pulmonary nontuberculous mycobacterial disease but not in pulmonary tuberculosis. These findings suggest that CA 19-9 may be a useful marker for monitoring therapeutic responses in pulmonary nontuberculous mycobacterial disease, although it is not pulmonary nontuberculous mycobacterial disease-specific marker.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000100026
Editor: | Brazilian Society of Infectious Diseases
Relação: | 10.1016/j.bjid.2015.09.005
Formato: | text/html
Fonte: | Brazilian Journal of Infectious Diseases  v.20 n.1 2016
Fonte: | info:eu-repo/semantics/openAccess