Data/hora: 08/06/2024 11:29:55

Provedor de dados: | Brazilian Journal of Infectious Diseases
País: | Brazil
Título: | Antimicrobials and renal failure in neutropenic patients
Autores: | França,Monique Sedlmaier; Lima,Stella Sala Soares; Duclou,Caroline Naback; Goulart,Eugênio Marcos Andrade; Romanelli,Roberta Maia de Castro.
Data: | 2013-08-01
Ano: | 2013
Palavras-chave: | Neutropenia; Renal insufficiency; Antimicrobial agents.
Resumo: | Antimicrobial treatment is often indicated to neutropenic patients. Although renal failure is a common complication of many antibiotics, no information could be found in the literature defining which are the best screening criteria for detecting renal injury. In this paper, the authors aim to assess the progress to renal failure in neutropenic patients on antimicrobial use and to compare different diagnostic criteria of renal failure in association to antimicrobial agents used. This is a cohort study conducted from February to August 2006 at the Hospital das Clínicas of the Universidade Federal de Minas Gerais, which included patients with neutropenia and antimicrobial therapy for the treatment of Healthcare Associated Infections notified by the Hospital Infection Control Committee. Renal injury has ensued in 25% of patients and no statistical difference between distinct criteria for renal injury was observed. Association of greater number of antimicrobials was associated with renal impairment. Time required for renal injury was independent of the antimicrobial regimen used, but mortality among patients with renal injury was higher when compared to those who had preserved renal function.
Tipo: | Info:eu-repo/semantics/other
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000400016
Editor: | Brazilian Society of Infectious Diseases
Relação: | 10.1016/j.bjid.2012.12.007
Formato: | text/html
Fonte: | Brazilian Journal of Infectious Diseases  v.17 n.4 2013
Fonte: | info:eu-repo/semantics/openAccess