Data/hora: 02/06/2024 06:57:22

Provedor de dados: 	55	
País: 	Brazil	
Título: 	Prolonged lymphocytosis as the first manifestation of Hodgkin-like adult T-cell leukemia/lymphoma	
Autores: 	Bittencourt,Achiléa L.; Andrade,Agnes Carvalho; Requião,Cristiane; Arruda,Maria da Gloria Bomfim; Araújo,Iguaracyra.	
Data: 	2017-02-01	
Ano: 	2017	
Palavras-chave: 	Adult T-cell leukemia/lymphoma; HTLV-1 infection; Pulmonary tuberculosis; Hodgkin-like ATLL.	
Resumo: 	Abstract Hodgkin-like ATLL is a rare variant of adult T-cell leukemia/lymphoma (ATLL), a disease caused by human T-cell lymphotropic virus type-1 (HTLV-1). At admission, a 46-year-old female presented with lymphadenomegaly, lymphocytosis, slight elevation of LDH blood level, and acid-alcohol resistant bacilli in sputum and was being treated for pulmonary tuberculosis (Tb). She had lymphocytosis in the previous 20 months. Serology for HTLV-1 was positive. Lymph node was infiltrated by medium-sized lymphocytes with scattered Hodgkin and Reed-Sternberg-like cells CD30+, CS1-4+, and CD79a+. Background cells were CD4+ and CD25+. A clinical diagnosis of favorable chronic ATLL was given. She was treated with chemotherapy but later progressed to acute ATLL and ultimately died. Hodgkin-like ATLL should be considered in the histological differential diagnosis with Hodgkin lymphoma since treatment and prognosis of these diseases are distinct. It is also important to search for HTLV-1 infection in patients with unexplained prolonged lymphocytosis.	
Tipo: 	Info:eu-repo/semantics/report	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702017000100119	
Editor: 	Brazilian Society of Infectious Diseases	
Relação: 	10.1016/j.bjid.2016.09.005	
Formato: 	text/html	
Fonte: 	Brazilian Journal of Infectious Diseases  v.21 n.1 2017	
Fonte: 	info:eu-repo/semantics/openAccess