Data/hora: 09/06/2024 06:40:55

Provedor de dados: 	55	
País: 	Brazil	
Título: 	Seroprevalence of hepatitis E virus in chronic hepatitis C in Brazil	
Autores: 	Bricks,Guilherme; Senise,Jorge Figueiredo; Pott Junior,Henrique; Grandi,Giuliano; Passarini,Amanda; Caldeira,Débora Bellini; Carnaúba Junior,Dimas; Moraes,Hamilton Antonio Bonilha de; Granato,Celso Franscisco Hernandes; Castelo,Adauto.	
Data: 	2018-03-01	
Ano: 	2018	
Palavras-chave: 	Hepatitis E virus; Hepatitis C virus; Brazil; Seroprevalence.	
Resumo: 	ABSTRACT  Background and aims: Hepatitis E virus infection in patients with underlying chronic liver disease is associated with liver decompensation and increased lethality. The seroprevalence of hepatitis E virus in patients with chronic hepatitis C in Brazil is unknown. This study aims to estimate the seroprevalence of hepatitis E virus in patients with chronic hepatitis C and to describe associated risk factors.  Methods: A total of 618 patients chronically infected with hepatitis C virus from three reference centers of São Paulo, Brazil were included. Presence of anti-HEV IgG was assessed by enzyme-linked immunosorbent assay (WANTAI HEV-IgG ELISA).  Results: Out of the 618 patients tested, 10.2% turned out positive for anti-HEV IgG (95% CI 8.0–12.8%). Higher seroprevalence was found independently associated with age over 60 years (OR = 2.04; p = 0.02) and previous contact with pigs (OR = 1.99; p = 0.03).  Conclusions: Patients with chronic hepatitis C are under risk of hepatitis E virus superinfection in São Paulo. Contact with pigs is a risk factor for the infection, suggesting a possible zoonosis with oral transmission.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000200085	
Editor: 	Brazilian Society of Infectious Diseases	
Relação: 	10.1016/j.bjid.2018.02.001	
Formato: 	text/html	
Fonte: 	Brazilian Journal of Infectious Diseases  v.22 n.2 2018	
Fonte: 	info:eu-repo/semantics/openAccess