Data/hora: 10/06/2024 19:12:45

Provedor de dados: 	55	
País: 	Brazil	
Título: 	KPC-producing Enterobacter aerogenes infection	
Autores: 	Tuon,Felipe F.; Scharf,Camila; Rocha,Jaime L.; Cieslinsk,Juliette; Becker,Guilherme Nardi; Arend,Lavinia N.	
Data: 	2015-06-01	
Ano: 	2015	
Palavras-chave: 	KPC Enterobacter; Carbapenemase; Infection control.	
Resumo: 	Background: Enterobacteris a common nosocomial microorganism and its carbapenem's resistance has increased. The management of these cases is unclear.Objective: We evaluated 16 patients with KPC-producing Enterobacter aerogenesinfections, detailing the site of infection, therapy, clinical and epidemiological data.Methods: A retrospective and descriptive study. Clinical data were revised and KPC-2 detection was by molecular methods. Risk factors associated with mortality were compared using appropriate tests according to variable type with a significance level of 0.05.Results: The 30-day mortality rate was 37.5% with no association with inadequate treatment. Age (p= 0.004) and Charlson score of comorbidities (p= 0.048) were independent risk factors associated with death in the multivariate analysis. The odds ratio for age &gt;43 years was 3.00 (95% CI: 1.02-9.32) and for Charlson score &gt;3 was 2.00 (95% CI: 1.08-3.71). Five strains were pan-resistant based on automated susceptibility tests. All patients were treated with monotherapy.Conclusion: The clinician should be alert to carbapenem-resistant Enterobacteriaceaeinfection in older patients with comorbidities. The mortality is high and we believe that prompt and adequate therapy must be employed.	
Tipo: 	Info:eu-repo/semantics/other	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702015000300324	
Editor: 	Brazilian Society of Infectious Diseases	
Relação: 	10.1016/j.bjid.2015.01.003	
Formato: 	text/html	
Fonte: 	Brazilian Journal of Infectious Diseases  v.19 n.3 2015	
Fonte: 	info:eu-repo/semantics/openAccess