Data/hora: 10/06/2024 14:01:19

Provedor de dados: 	55	
País: 	Brazil	
Título: 	Seroprevalence of chikungunya virus infection in five hospitals within Anyigba, Kogi State of Nigeria	
Autores: 	Omatola,Cornelius A.; Onoja,Bernard A.; Fassan,Peter K.; Osaruyi,Stephanie A.; Iyeh,Mercy; Samuel,Matthew A.; Haruna,Peace U.	
Data: 	2020-02-01	
Ano: 	2020	
Palavras-chave: 	Chikungunya; Fever; Seroprevalence; IgM; IgG; Nigeria.	
Resumo: 	ABSTRACT Febrile illnesses in developing countries are often misdiagnosed as malaria or typhoid fever. Although arboviral infections have similar clinical symptoms, they are usually not screened because of limited resources and the fact that there are several viruses in this group. Chikungunya virus (CHIKV) has been isolated in parts of Nigeria, but there is no documented evidence of the infection in Kogi State. This study determined seroprevalence of active and past CHIKV infection among febrile patients who tested negative for malaria and typhoid fever. Sera from 243 febrile patients were screened for CHIKV IgG and IgM using an immunochromatographic test kit. Clinical and socio-demographic variables were collected using a structured questionnaire. Recent CHIKV infection was observed in 5.8% of the study participants while 25.1% had IgG antibodies demonstrating previous infection. Significant associations were observed between seropositivity and age of participants (p &lt; 0.001), sex (p = 0.044), marital status (p = 0.002), and occupation (p &lt; 0.001). Clinical symptoms such as fever, joint pain, and headache were significantly associated with seropositivity. This study identified recent CHIKV infection in Anyigba. Therefore, there is need for routine screening of febrile patients and molecular characterization to determine the nature of circulating strains.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702020000100001	
Editor: 	Brazilian Society of Infectious Diseases	
Relação: 	10.1016/j.bjid.2020.01.001	
Formato: 	text/html	
Fonte: 	Brazilian Journal of Infectious Diseases  v.24 n.1 2020	
Fonte: 	info:eu-repo/semantics/openAccess