Data/hora: 09/06/2024 03:50:07

Provedor de dados: | Brazilian Journal of Infectious Diseases
País: | Brazil
Título: | Impact of A/H1N1 influenza in children at a Brazilian University Hospital
Autores: | Biondo,Gabriela Fontanella; Santana,João Carlos; Lago,Patrícia M.; Piva,Jefferson; Souza,Paulo Ricardo A.; Gaulke,Joana Genz; Sebben,Juliana M.
Data: | 2018-06-01
Ano: | 2018
Palavras-chave: | H1N1 influenza; Emergency; Critical care; Children.
Resumo: | ABSTRACT  Background A/H1N1 influenza is a viral disease that affects a significant part of the population mainly in winter, leading to increased number of medical consultations, hospitalizations and consequently care spending in emergency.  Methods This is a case-series retrospective study, involving patients admitted to a tertiary hospital in southern Brazil in 2016 with a clinical diagnosis of acute respiratory infection of the influenza type and laboratory confirmation of influenza A/H1N1.  Results 64 patients were included, mostly male, median age of 48.3 months. Chronic underlying diseases were found in 73% of the patients, and these patients evolved to the most unfavorable outcome. About vaccination, of the 57 patients with an age range for vaccination, only 28% had complete vaccination coverage. The main clinical manifestations found in the included patients were fever, cough, intercostal indrawing, wheezing, tachypnea and pulmonary crackles. These patients were mainly followed-up with laboratory tests and chest X-ray. Consolidation was evident in 43% of patients followed by interstitial infiltrate in 33%. A five-day course of neuraminidase inhibitor was prescribed for all patients, as recommended by the WHO, but due to the complications, 73% of the patients required antibiotic therapy, and 61% oxygen therapy. The majority of patients had a favorable outcome, but 11 required intensive care and one died.  Conclusions A/H1N1 influenza persists as an important public health problem, mainly due to high morbidity and hospitalization rates. It is important to identify patients with A/H1N1 influenza and clinical situations with higher risk of complications. Through this study, it is possible to analyze the characteristics of pediatric patients with A/H1N1 influenza and mainly to emphasize assistance of populations with comorbidities, since they present higher rates of complications and death.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000300219
Editor: | Brazilian Society of Infectious Diseases
Relação: | 10.1016/j.bjid.2018.05.004
Formato: | text/html
Fonte: | Brazilian Journal of Infectious Diseases  v.22 n.3 2018
Fonte: | info:eu-repo/semantics/openAccess