Data/hora: 11/06/2024 06:43:05

Provedor de dados: | 55
País: | Brazil
Título: | Successful treatment of pulmonary Nocardia farcinica infection with linezolid: case report and literature review
Autores: | Shen,Tian; Wu,Lihua; Geng,Lei; Wei,Zeqing; Zheng,Shusen.
Data: | 2011-10-01
Ano: | 2011
Palavras-chave: | Nocardia; Linezolid; Drug therapy; Transplantation.
Resumo: | Nocardia infection is rare but potentially fatal. Therapy of Nocardia infection remains difficult. Linezolid, a novel oxazolidinone antibiotic, has proven to be effective, but clinical data are limited. Here we describe a case of a 45-year-old man with pulmonary N. farcinica infection following a liver transplantation. The initial therapy was trimethoprim-sulfamethoxazole, which showed no effect. According to susceptibility test, linezolid was administered with clearly improving the patient's condition. The treatment was stopped for anemia as drug related adverse event, and the therapy lasted for as long as 5 months. At the end of treatment clinical cure was confirmed and anemia reversed after discontinuation of linezolid. We also analyzed the clinical data of previously published reports by literature review, focusing on the efficacy and safety of linezolid treatment for Nocardia infection.
Tipo: | Info:eu-repo/semantics/report
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000500014
Editor: | Brazilian Society of Infectious Diseases
Relação: | 10.1590/S1413-86702011000500014
Formato: | text/html
Fonte: | Brazilian Journal of Infectious Diseases  v.15 n.5 2011
Fonte: | info:eu-repo/semantics/openAccess