Data/hora: 13/06/2024 19:13:37

Provedor de dados: | 55
País: | Brazil
Título: | Detection and molecular characterization of β-lactamase genes in clinical isolates of Gram-negative bacteria in Southern Ecuador
Autores: | Delgado,Diana Yessenia Calva; Barrigas,Zorayda Patricia Toledo; Astutillo,Sofía Genoveva Ochoa; Jaramillo,Ana Paulina Arévalo; Ausili,Alessio.
Data: | 2016-12-01
Ano: | 2016
Palavras-chave: | Β-Lactam resistance; Β-Lactamase; ESBL; Genotypic characterization.
Resumo: | ABSTRACT This work performed a phenotypic and genotypic characterization of 79 clinical isolates of Enterobacteriaceae and Pseudomonadaceae collected in hospitals of Southern Ecuadorin 2013. Our results showed a high incidence of β-lactamases and ESBLs with blaTEM and blaCTX-M as the prevalent genes, respectively. By direct sequencing of PCR amplicons, the different β-lactamases and variants of the genes were also distinguished. Our results revealed a predominance of TEM-1 β-lactamase and the presence of different CTX-M variants with a prevalence of CTX-M-15. Two infrequent CTX-M variants in South America were also identified. To the best of our knowledge, this is one of the first studies describing the genetic characteristics of β-lactamases in Ecuador.
Tipo: | Info:eu-repo/semantics/other
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000600627
Editor: | Brazilian Society of Infectious Diseases
Relação: | 10.1016/j.bjid.2016.07.001
Formato: | text/html
Fonte: | Brazilian Journal of Infectious Diseases  v.20 n.6 2016
Fonte: | info:eu-repo/semantics/openAccess