Data/hora: 11/06/2024 11:19:06

Provedor de dados: 	Brazilian Journal of Infectious Diseases	
País: 	Brazil	
Título: 	Methicillin-resistant Staphylococcus aureus nasal carriage in neonates and children attending a pediatric outpatient clinics in Brazil	
Autores: 	Vieira,Maria Aparecida; Minamisava,Ruth; Pessoa-Júnior,Vicente; Lamaro-Cardoso,Juliana; Ternes,Yves Mauro; Andre,Maria Cláudia Porfirio; Sgambatti,Sabrina; Kipnis,André; Andrade,Ana Lúcia.	
Data: 	2014-01-01	
Ano: 	2014	
Palavras-chave: 	Staphylococcus aureus carriage; Methicillin-resistant Staphylococcus; Aureus; Neonates; Children.	
Resumo: 	Background:In Latin America, few studies have been carried out on methicillin-resistant Staphylococcus aureus carriage in the pediatric population. We conducted a survey of nasal S. aureus carriage in neonates and in children attending the pediatric outpatient clinics in a large Brazilian city with high antimicrobial consumption.Methods:Pernasal swabs of neonates were collected upon admission and at discharge in four neonatal intensive care units and of children less than five years of age during outpatient visits. Methicillin-resistant S. aureus isolates were characterized for antibiotic susceptibility, mec gene presence, pulsed-field gel electrophoresis, spatype, SCCmec-type, multilocus sequence type, and presence of Panton-Valentine leukocidin genes.Results:S. aureus was carried by 9.1% and 20.1% of the 701 neonates and of 2034 children attending the outpatient clinics, respectively; methicillin-resistant S. aureus carriage was detected in 0.6% and 0.2%, of the these populations, respectively. Healthcare-associated methicillin-resistant S. aureus strains found in neonates from neonatal intensive care units and outpatients were genetically related to the Brazilian (SCCmec-III, ST239) and to the Pediatric (SCCmec-IV, ST5) clones. Community-associated methicillin-resistant S. aureus was only detected in outpatients. None of the methicillin-resistant S. aureus strains contained the Panton-Valentine leukocidin gene. Methicillin-resistant S. aureus strains related to the Brazilian clone showed multidrug resistance pattern.Conclusions:Despite the high antibiotic pressure in our area, and the cross transmission of the healthcare-associated methicillin-resistant S. aureus clones between neonatal intensive care units and outpatients, the prevalence of methicillin-resistant S. aureus carriage is still low in our setting.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000100042	
Editor: 	Brazilian Society of Infectious Diseases	
Relação: 	10.1016/j.bjid.2013.04.012	
Formato: 	text/html	
Fonte: 	Brazilian Journal of Infectious Diseases  v.18 n.1 2014	
Fonte: 	info:eu-repo/semantics/openAccess