Data/hora: 10/06/2024 16:07:17

Provedor de dados: | 55
País: | Brazil
Título: | Antibiotics produced by Streptomyces
Autores: | Procópio,Rudi Emerson de Lima; Silva,Ingrid Reis da; Martins,Mayra Kassawara; Azevedo,João Lúcio de; Araújo,Janete Magali de.
Data: | 2012-10-01
Ano: | 2012
Palavras-chave: | Streptomyces; Antibiotics; Resistance; Infection.
Resumo: | Streptomyces is a genus of Gram-positive bacteria that grows in various environments, and its shape resembles filamentous fungi. The morphological differentiation of Streptomyces involves the formation of a layer of hyphae that can differentiate into a chain of spores. The most interesting property of Streptomyces is the ability to produce bioactive secondary metabolites, such as antifungals, antivirals, antitumorals, anti-hypertensives, immunosuppressants, and especially antibiotics. The production of most antibiotics is species specific, and these secondary metabolites are important for Streptomyces species in order to compete with other microorganisms that come in contact, even within the same genre. Despite the success of the discovery of antibiotics, and advances in the techniques of their production, infectious diseases still remain the second leading cause of death worldwide, and bacterial infections cause approximately 17 million deaths annually, affecting mainly children and the elderly. Self-medication and overuse of antibiotics is another important factor that contributes to resistance, reducing the lifetime of the antibiotic, thus causing the constant need for research and development of new antibiotics.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000500011
Editor: | Brazilian Society of Infectious Diseases
Relação: | 10.1016/j.bjid.2012.08.014
Formato: | text/html
Fonte: | Brazilian Journal of Infectious Diseases  v.16 n.5 2012
Fonte: | info:eu-repo/semantics/openAccess