Data/hora: 11/06/2024 14:44:05

Provedor de dados: 	55	
País: 	Brazil	
Título: 	What is the probability of a patient presenting a pleural effusion due to tuberculosis?	
Autores: 	Neves,Denise Duprat; Dias,Ricardo Marques; Cunha,Antônio José Ledo Alves da; Preza,Paulo César Amorim.	
Data: 	2004-08-01	
Ano: 	2004	
Palavras-chave: 	Bayes' Theorem; Tuberculosis; Pleural effusion; Adenosine deaminase and diagnosis.	
Resumo: 	INTRODUCTION: In Rio de Janeiro, in almost half of the cases of pleural tuberculosis (PT) treatment begins without substantiation of diagnosis. We examined variables associated with this disease. METHOD: We studied 215 consecutive patients; 104 had tuberculosis (TB) and 111 did not (NTB): 41 neoplasms, 29 transudates, 28 para-pneumonic and 13 other etiologies. Clinical and laboratory variables were assessed in a combined manner using likelihood ratios (LR) and Bayes' theorem to determine the probability of PT. RESULTS: Among the variables examined, adenosine deaminase (ADA) levels, lymphocyte cell percentage, protein and age were the best indicators for the diagnosis of PT. Association of ADA with any of the other variables led to a LR+ higher than 10 and a LR- lower than 0.1, indicating the presence or absence of PT, with an individual probability of more than 90% or of less than 10% considering that there was a 50% initial probability associated with the presence of PT. CONCLUSIONS: Since ADA is highly sensitive, we can practically exclude TB as the cause of effusion when there are low ADA values. However, to confirm the possibility of TB we recommend that other variables, such as prevalence of lymphocytes (higher than 90%), and high protein levels (more than 4g/dL); low age (less than 45 years) also should be considered.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702004000400007	
Editor: 	Brazilian Society of Infectious Diseases	
Relação: 	10.1590/S1413-86702004000400007	
Formato: 	text/html	
Fonte: 	Brazilian Journal of Infectious Diseases  v.8 n.4 2004	
Fonte: 	info:eu-repo/semantics/openAccess