Data/hora: 10/06/2024 01:23:06

Provedor de dados: | 55
País: | Brazil
Título: | The impact of dengue on liver function as evaluated by aminotransferase levels
Autores: | Souza,Luiz José de; Nogueira,Rita Maria Ribeiro; Soares,Leandro Cordeiro; Soares,Carlos Eduardo Cordeiro; Ribas,Bruno Fernandes; Alves,Felipe Pinto; Vieira,Fabíola Rodrigues; Pessanha,Felipe Eulálio Baldi.
Data: | 2007-08-01
Ano: | 2007
Palavras-chave: | Dengue; Dengue hemorrhagic fever; Aminotransferases; Hepatitis.
Resumo: | The objective of this study was to evaluate the impact of dengue virus infection on liver function by measuring aminotransferase in blood samples from patients serologically diagnosed by according to two MAC-ELISA protocols. Degrees of liver damage were classified according to aminotransferase levels: grade A - normal enzyme levels; grade B - increased levels of at least one of the enzymes; grade C - increased, with at least one of the enzymes being at levels higher than three times the upper reference values; grade D - acute hepatitis, with aminotransferase levels at least ten times their normal values. Of the 169 serologically confirmed cases of dengue at the dengue referral center in Campos dos Goytacazes in the state of Rio de Janeiro, Brazil, 65.1% had abnormal aminotransferase levels: 81 cases being classified as grade B, 25 as grade C and 3 as grade D. A further 34.9% of cases had normal enzyme levels and were classified as grade A. Liver damage is a common complication of dengue infection and aminotransferase levels are a valuable marker for monitoring these cases.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000400007
Editor: | Brazilian Society of Infectious Diseases
Relação: | 10.1590/S1413-86702007000400007
Formato: | text/html
Fonte: | Brazilian Journal of Infectious Diseases  v.11 n.4 2007
Fonte: | info:eu-repo/semantics/openAccess