Data/hora: 01/06/2024 17:36:32

Provedor de dados: | 55
País: | Brazil
Título: | High prevalence of hepatitis C associated with familial history of hepatitis in a small town of south Brazil: efficiency of the rapid test for epidemiological survey
Autores: | Ivantes,Cláudia Alexandra Pontes; Silva,Danilo; Messias-Reason,Iara.
Data: | 2010-10-01
Ano: | 2010
Palavras-chave: | Hepatitis C; Epidemiology; Brazil.
Resumo: | This report describes a cross-sectional survey on the prevalence of hepatitis C antibodies (anti-HCV) in Tamboara, a small community in the northwest area from Paraná State, south of Brazil with a high rate of accumulated detection for HCV. Eight hundred and sixteen residents (17.87% from all the population), independently of the age and time living in Tamboara were included in this study by an epidemiologic questionnaire and by testing for anti-HCV. The rapid immuno-chromatographic test was applied for detection of HCV antibodies. The anti-HCV prevalence by rapid test was 4.28%. The median age for positive and negative test was 60.49 ± 14.14 and 41.67 ± 20.25, respectively (p &lt; 0.001). By multivariate analysis, only familial history of hepatitis (p = 0.001; OR = 6.41; CI 95% = 2.08-19.78) and age (p = 0.007; OR 1.06;95% CI = 1.02-1.10) showed statistical significance for positive anti-HCV. The rapid test sensitivity and specificity were 100% and 92.7% respectively, with an accuracy of 95.8% (95% CI = 91-100). These findings demonstrated a high prevalence of anti-HCV in Tamboara. The familial history of hepatitis was a significant risk factor to the infection and HCV rapid test showed to be accurate and feasible for epidemiological survey
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000500010
Editor: | Brazilian Society of Infectious Diseases
Relação: | 10.1590/S1413-86702010000500010
Formato: | text/html
Fonte: | Brazilian Journal of Infectious Diseases  v.14 n.5 2010
Fonte: | info:eu-repo/semantics/openAccess