Data/hora: 06/06/2024 00:20:03

Provedor de dados: 	55	
País: 	Brazil	
Título: 	Perinatal morbidity and mortality associated with chlamydial infection: a meta-analysis study	
Autores: 	Silva,Maria José Penna Maisonnette de Attayde; Florêncio,Gilzandra Lira Dantas; Gabiatti,José Roberto Erbolato; Amaral,Rose Luce do; Eleutério Júnior,José; Gonçalves,Ana Katherine da Silveira.	
Data: 	2011-12-01	
Ano: 	2011	
Palavras-chave: 	Chlamydia trachomatis; Perinatal mortality; Morbidity; Meta-analysis.	
Resumo: 	OBJECTIVE: To evaluate the effect of Chlamydia trachomatis infection during pregnancy on perinatal morbidity and mortality. METHODS: Systematic review and meta-analysis in an electronic database and manual, combining high sensitivity specific descriptors seeking to answer the research objective. The articles considered to be of high methodological quality (score above 6 on the Newcastle-Ottawa Scale) were assessed by meta-analysis. RESULTS: Summary estimates of 12 studies were calculated by means of Mantel-Haenszel test with 95% confidence interval. It was observed that Chlamydia infection during pregnancy increased risk of preterm labor (relative risk (RR) = 1.35 [1.11, 1.63]), low birth weight (RR = 1.52 [1.24, 1.87]) and perinatal mortality (RR = 1.84 [1.15, 2.94]). No evidence of increased risk was associated with Chlamydia infection in regard to premature rupture of membranes (RR = 1.13 [0.95, 1.34]), abortion and postpartum endometritis (RR = 1.20 [0.65, 2.20] and 0.89 [0.49, 1.61] respectively). CONCLUSION: The diagnosis and treatment of Chlamydia cervicitis during pregnancy can reduce perinatal morbidity and mortality associated with this infection. However, clinical trials are needed to confirm these findings.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000600006	
Editor: 	Brazilian Society of Infectious Diseases	
Relação: 	10.1590/S1413-86702011000600006	
Formato: 	text/html	
Fonte: 	Brazilian Journal of Infectious Diseases  v.15 n.6 2011	
Fonte: 	info:eu-repo/semantics/openAccess