Data/hora: 09/06/2024 16:41:05

Provedor de dados: | 55
País: | Brazil
Título: | Clinical and microbiological characterization of KPC-producing Klebsiella pneumoniae infections in Brazil
Autores: | Beirão,Elisa Maria; Furtado,Juvencio Jose Duailibe; Girardello,Raquel; Ferreira Filho,Heli; Gales,Ana Cristina.
Data: | 2011-02-01
Ano: | 2011
Palavras-chave: | Klebsiella pneumonia; KPC; Hospital infection; Carbapenemase.
Resumo: | In 2008 isolates of KPC-producing Klebsiella pneumoniae (KPC-KPN) were detected for the first time at Hospital Heliópolis, São Paulo, Brazil. The aim of this study was to characterize the clinical and microbiological outcomes of infections caused by KPC-KPN. A historical cohort of patients from whom KPC-KPN strains were isolated was performed. Isolates were identified as resistant to ertapenem by automated broth microdilution system and screened as carbapenemase producers by the modified Hodge test. The beta-lactamase resistance gene blaKPC was detected by PCR. The genetic relatedness of isolates was determined by PFGE. The study provides early clinical experience in treating KPC-KPN infections in a Brazilian tertiary center.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000100013
Editor: | Brazilian Society of Infectious Diseases
Relação: | 10.1590/S1413-86702011000100013
Formato: | text/html
Fonte: | Brazilian Journal of Infectious Diseases  v.15 n.1 2011
Fonte: | info:eu-repo/semantics/openAccess