Data/hora: 10/06/2024 07:41:34

Provedor de dados: | 55
País: | Brazil
Título: | Human immunodeficiency virus and hepatitis C virus/hepatitis B virus co-infection in Southern Brazil: clinical and epidemiological evaluation
Autores: | Raboni,Sonia Mara; Tuon,Felipe Francisco; Beloto,Nayara Carvalho Polido; Demeneck,Henrique; Oliveira,Andre; Largura,Denis; Sagrado,Andressa Gervasoni; Lima,Bárbara Perdonsini; Franzoni,João Paulo; Pedroso,Maria Lucia.
Data: | 2014-12-01
Ano: | 2014
Palavras-chave: | Human immunodeficiency virus; Hepatitis B; Hepatitis C; Co-infection.
Resumo: | Hepatitis B virus, hepatitis C virus and human immunodeficiency virus share a similar transmission pathway and are often diagnosed in the same patient. These patients tend to have a faster progression of hepatic fibrosis. This cross-sectional study describes the demographic features and clinical profile of human immunodeficiency virus/hepatitis co-infected patients in Parana, Southern Brazil. A total of 93 human immunodeficiency virus-infected patients attending a tertiary care academic hospital in Southern Brazil were included. Clinical, demographic and epidemiological data were evaluated. Hepatitis B virus and/or hepatitis C virus positive serology was found in 6.6% of patients. The anti-hepatitis C virus serum test was positive in 85% (79/93) of patients, and the infection was confirmed in 72% of the cases. Eighteen patients (19%) were human immunodeficiency virus/hepatitis B virus positive (detectable HBsAg). Among co-infected patients, there was a high frequency of drug use, and investigations for the detection of co-infection were conducted late. A low number of patients were eligible for treatment and, although the response to antiretroviral therapy was good, there was a very poor response to hepatitis therapy. Our preliminary findings indicate the need for protocols aimed at systematic investigation of hepatitis B virus and hepatitis C virus in human immunodeficiency virus-infected patients, thus allowing for early detection and treatment of co-infected patients.
Tipo: | Info:eu-repo/semantics/report
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000600664
Editor: | Brazilian Society of Infectious Diseases
Relação: | 10.1016/j.bjid.2014.05.011
Formato: | text/html
Fonte: | Brazilian Journal of Infectious Diseases  v.18 n.6 2014
Fonte: | info:eu-repo/semantics/openAccess