Data/hora: 11/06/2024 12:27:39

Provedor de dados: | 55
País: | Brazil
Título: | Health care workers humoral immune response against GLcB, MPT51 and HSPX from Mycobacterium tuberculosis
Autores: | Reis,Michelle Cristina Guerreiro dos; Rabahi,Marcelo Fouad; Kipnis,André; Junqueira-Kipnis,Ana Paula.
Data: | 2009-12-01
Ano: | 2009
Palavras-chave: | Latent tuberculosis; Infection; Antibodies.
Resumo: | Tuberculosis (TB) is one of the oldest human infectious diseases and one third of the world's population is latently infected. Brazil is an endemic area for TB. One of the most important challenges in TB control is the identification of latently infected individuals. Health Care Workers (HCW) are at high risk of being infected with Mycobacterium tuberculosis and even to become TB latently infected. The aim of this study was to increase knowledge about humoral immune response in TB latently infected individuals. HCW were classified according to their tuberculin skin test (TST), as positive or negative. The antibody response to GLcB, MPT51 and HSPX from Mycobacterium tuberculosis was evaluated. TST negative HCW constituted the majority of those who showed a humoral immune response. Antibody levels varied according to antigen characteristics, TST and BCG status. We suggest that possibly the presence of those antibodies could have a function in the protective immune response against Mycobacterium tuberculosis.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702009000600006
Editor: | Brazilian Society of Infectious Diseases
Relação: | 10.1590/S1413-86702009000600006
Formato: | text/html
Fonte: | Brazilian Journal of Infectious Diseases  v.13 n.6 2009
Fonte: | info:eu-repo/semantics/openAccess