Data/hora: 11/06/2024 04:08:23

Provedor de dados: | Brazilian Journal of Infectious Diseases
País: | Brazil
Título: | Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosum
Autores: | Morais,Orlando Oliveira de; Porto,Cláudia; Coutinho,Anglya Samara Silva Leite; Reis,Carmélia Matos Santiago; Teixeira,Marcus de Melo; Gomes,Ciro Martins.
Data: | 2011-06-01
Ano: | 2011
Palavras-chave: | HIV; Pneumonia; Macrolides; Mortality.
Resumo: | Aureobasidium pullulans is a causal agent of phaeohyphomycosis, occasionally found in men and animals. As an agent of different opportunistic fungal processes, it may cause fungemia, systemic infections and abscesses in different viscera. This paper aims to report a case of a patient with infection of the lymphatic system by A. pullulans. A 23-year-old patient being treated for erythema nodosum leprosum presented a 60-day complaint of daily fever, hoarseness, odynophagia and weight loss. Laboratory tests showed pancytopenia with severe neutropenia, cervical adenomegaly and solid contrast uptake lesion in the oropharyngeal region. Due to neutropenia and sepsis the patient was initially treated with cefepime and vancomycin, but there was no clinical improvement. Lymph node puncture-aspiration showed yeast-form fungus identified as A. pullulans by sequencing ITS region. The patient was treated with amphotericin B deoxycholate, leading to complete recovery of bone marrow function and regression of adenomegaly and the oropharyngeal lesion.
Tipo: | Info:eu-repo/semantics/report
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000300019
Editor: | Brazilian Society of Infectious Diseases
Relação: | 10.1590/S1413-86702011000300019
Formato: | text/html
Fonte: | Brazilian Journal of Infectious Diseases  v.15 n.3 2011
Fonte: | info:eu-repo/semantics/openAccess