Data/hora: 09/06/2024 05:45:41

Provedor de dados: | Brazilian Journal of Infectious Diseases
País: | Brazil
Título: | Treatment outcome of human immunodeﬁciency virus and tuberculosis co-infected patients in public hospitals of eastern and southern zone of Tigray region, Ethiopia
Autores: | Belayneh,Mehretu; Giday,Kalayta; Lemma,Hailemariam.
Data: | 2015-02-01
Ano: | 2015
Palavras-chave: | Treatment outcome; TB/HIV co-infected; Tigray; Ethiopia.
Resumo: | Background:Tuberculosis is a leading cause of death among people living with human immunodeﬁciency virus. In sub-Saharan Africa, tuberculosis accounts for more than 78% of all deaths among people with human immunodeﬁciency virus.Objectives:To assess tuberculosis treatment outcome and the associated factors in adult tuberculosis/human immunodeﬁciency virus co-infected patients in four public hospitals of eastern and southern zone of Tigray region, Ethiopia.Methodology:Institution based cross-sectional study design was used to examine secondary data from tuberculosis/human immunodeﬁciency virus co-infected patients attending four public hospitals of eastern and southern zone of Tigray, from January 2009 to August 2011. Systematic random sampling technique was used to select individual patient cards from the respective hospitals. Univariate analysis and multivariate logistic regression modeling was used to assess the impact of each variable in predicting treatment outcome.Results:Out of 342 patients included, 199 (58.2%) patients completed treatment, 43 (12.6%) patients were cured, 88 (25.7%) died, 7 (2%) defaulted, and 5 (1.5%) patients failed treatment. Treatment success rate was around 71%. In the multivariate logistic regression analysis the factors that were strongly associated with unfavorable tuberculosis treatment outcomes were WHO stage IV (AOR = 3.2, CI = 1.58-6.82, p-value = 0.001), age greater than 45 years (AOR = 6.08, CI = 2.28-16.23) and baseline CD4 count less than 200 cells/L (AOR = 6.19, CI = 2.28-16.89, p-value = 0.001).Conclusion:The rate of treatment success in this study was lower than the rate newly recommended by WHO. Therefore, efforts should be undertaken to improve treatment success rates of both diseases.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702015000100047
Editor: | Brazilian Society of Infectious Diseases
Relação: | 10.1016/j.bjid.2014.09.002
Formato: | text/html
Fonte: | Brazilian Journal of Infectious Diseases  v.19 n.1 2015
Fonte: | info:eu-repo/semantics/openAccess