Data/hora: 11/06/2024 07:01:20

Provedor de dados: | Brazilian Journal of Infectious Diseases
País: | Brazil
Título: | Heterogeneous resistance to vancomycin and teicoplanin among Staphylococcus spp. isolated from bacteremia
Autores: | Nunes,Ana Paula Ferreira; Schuenck,Ricardo Pinto; Bastos,Carla Callegário Reis; Magnanini,Mônica Maria F.; Long,Jacinta B.; Iorio,Natália Lopes Pontes; Santos,Kátia Regina Netto dos.
Data: | 2007-06-01
Ano: | 2007
Palavras-chave: | Staphylococci; Vancomycin and teicoplanin heteroresistance; Population analysis profile; Vancomycin agar screen.
Resumo: | This study evaluated the BHIA screening method with 4 or 6 mug/mL of vancomycin to detect glycopeptides heteroresistant staphylococci strains isolated from bacteremia. A total of 213 staphylococci strains were isolated from 106 patients between October/2001 and November/2002 in a tertiary hospital in Rio de Janeiro city. Fifty-seven (53.8%) patients presented Staphylococcus aureus, while coagulase-negative staphylococci (CNS) were isolated from 49 (46.2%). Resistance rates for oxacillin of 26.3% and 81.6% were found for the staphylococci isolates, respectively. Thirteen CNS isolated from nine (8.5%) patients grew on agar screening with 4 mug/mL of vancomycin and showed heterogeneous profiles of resistance for vancomycin and teicoplanin by the population analysis profile method. Only 30.8% of them grew at the concentration 6 mug/mL. Bacterial infection and use of antimicrobial therapy were common among these patients. Alert about the emergence of oxacillin-resistant staphylococci presenting heteroresistance to glycopeptides is important in order to achieve judicious use of antimicrobials. Vancomycin agar screening test could help to confirm the presence of these isolates in hospitals.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000300009
Editor: | Brazilian Society of Infectious Diseases
Relação: | 10.1590/S1413-86702007000300009
Formato: | text/html
Fonte: | Brazilian Journal of Infectious Diseases  v.11 n.3 2007
Fonte: | info:eu-repo/semantics/openAccess