Data/hora: 01/06/2024 18:03:27

Provedor de dados: | Brazilian Journal of Infectious Diseases
País: | Brazil
Título: | Epidemiological and microbiological analysis of ventilator-associated pneumonia patients in a public teaching hospital
Autores: | Silva Júnior,João Manoel da; Rezende,Ederlon; Guimarães,Thaís; Campos,Edvaldo V. dos; Magno,Luiz André; Consorti,Lívia; Pereira,Renata Andréa Pietro; Nascimento,Maria de Lourdes; Mendonça,João Silva de.
Data: | 2007-10-01
Ano: | 2007
Palavras-chave: | Ventilator-associated pneumonia; Epidemiology; Microbiology.
Resumo: | Ventilator-associated pneumonia (VAP) is the most commonly-acquired infection in patients in intensive care units. We analyzed epidemiological and microbiological characteristics and the outcome, in a cohort of critically-ill patients with confirmed diagnosis of VAP. All patients who had been on mechanical ventilation (MV) for more than 48 hours were included in our study; material collection for microbiological analysis was done within the first 24 hours after beginning treatment or after changing antibiotics. There were 55/265 (20.7%) VAP cases diagnosed, at a rate of 21.6 episodes per 1,000 days of mechanical ventilation. Mean age of the patients was 66 years, with a mean APACHE II score of 26.7 + 7.0; male patients were more prevalent. The mortality rates in the intensive care unit (ICU) and during the hospital stay were 71% and 80%, respectively. MV duration in patients with VAP was 17 (range 3-43) days and among patients who had not developed VAP, 6 (2-32) days (p &lt; 0.0001). 98.2% of the samples were positive, with a high prevalence of Gram-negative bacteria, mainly Acinetobacter calcoaceticus. Risk factors for death included age, MV duration and surgery. VAP incidence in this sample of critically-ill patients was high, with a high mortality rate. Control and prevention strategies based on continuing education of healthcare workers, developed by a multidisciplinary team, should be encouraged to minimize morbimortality of this infection.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000500009
Editor: | Brazilian Society of Infectious Diseases
Relação: | 10.1590/S1413-86702007000500009
Formato: | text/html
Fonte: | Brazilian Journal of Infectious Diseases  v.11 n.5 2007
Fonte: | info:eu-repo/semantics/openAccess