Data/hora: 02/06/2024 06:48:04

Provedor de dados: | 55
País: | Brazil
Título: | A case study of disseminated histoplasmosis linked to common variable immunodeficiency
Autores: | Rachid,Acir; Rezende,Lucila Stange; Moura,Suzelle Freitas de; Loffy,Paulo C.; Magalhães,Francisco Luiz Gomide M.
Data: | 2003-08-01
Ano: | 2003
Palavras-chave: | Disseminated histoplasmosis; Common variable immunodeficiency; Immunoglobulins.
Resumo: | Histoplasma capsulatum, a ground fungus, can infect humans, normally in endemic areas; the resulting disease can be asymptomatic or it can have a benign development, but in rare cases it can develop into a serious clinical condition and can even be fatal. Its most characteristic initial location is in the lungs, resembling tuberculosis, often accompanied by mediastinitis and an exuberant fibrotic response. The spread of this infection can be caused by the concomitance of another illness that alters the immunological balance. Sometimes such an association is not clear. Therefore, disseminated histoplasmosis is defined as a clinical condition where the fungus is present in more than one location. Common variable immunodeficiency is characterized by a generalized failure in the synthesis of antibodies, leading the affected individuals to present recurrent infections, especially those caused by encapsulated bacteria, most often involving the respiratory tract. We studied a serious case of disseminated histoplasmosis, accompanied by common variable immunodeficiency, observed at the Infirmary of the department of Medical Practice of the Federal University at Paraná Hospital das Clínicas.
Tipo: | Info:eu-repo/semantics/report
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702003000400007
Editor: | Brazilian Society of Infectious Diseases
Relação: | 10.1590/S1413-86702003000400007
Formato: | text/html
Fonte: | Brazilian Journal of Infectious Diseases  v.7 n.4 2003
Fonte: | info:eu-repo/semantics/openAccess