Data/hora: 04/06/2024 12:33:38

Provedor de dados: | Brazilian Journal of Infectious Diseases
País: | Brazil
Título: | Molecular and clinical evaluation of the acute human parvovirus B19 infection: comparison of two cases in children with sickle cell disease and discussion of the literature
Autores: | Slavov,Svetoslav Nanev; Kashima,Simone; Silva-Pinto,Ana Cristina; Amarilla,Alberto Anastacio; Aquino,Victor Hugo; Covas,Dimas Tadeu.
Data: | 2013-02-01
Ano: | 2013
Palavras-chave: | Human parvovirus B19; Viral load; Aplastic crisis; Subgenotypes.
Resumo: | Human parvovirus B19 is a well-known cause of severe conditions in patients with sickle cell disease, but the molecular mechanisms of the infection are insufficiently understood. The different clinical outcome of the acute parvovirus B19 infection in two pediatric patients with sickle cell disease has been examined. One of them developed life-threatening condition requiring emergency transfusions, while the other had asymptomatic infection, diagnosed occasionally. Both cases had high viral load and identical subgenotype, indicating that the viral molecular characteristics play a minimal role in the infection outcome.
Tipo: | Info:eu-repo/semantics/report
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000100017
Editor: | Brazilian Society of Infectious Diseases
Relação: | 10.1016/j.bjid.2012.06.026
Formato: | text/html
Fonte: | Brazilian Journal of Infectious Diseases  v.17 n.1 2013
Fonte: | info:eu-repo/semantics/openAccess