Data/hora: 13/06/2024 07:56:52

Provedor de dados: | Brazilian Journal of Infectious Diseases
País: | Brazil
Título: | Staphylococcus aureus bacteremia: comparison of two periods and a predictive model of mortality
Autores: | Conterno,Lucieni de Oliveira; Wey,Sérgio Barsanti; Castelo,Adauto.
Data: | 2002-12-01
Ano: | 2002
Palavras-chave: | Staphylococcus aureus; Bacteremia; Mortality.
Resumo: | Staphylococcus aureus is an important pathogen causing bacteremia, primarily affecting hospitalized patients. We studied the epidemiology of S. aureus bacteremia, comparing two periods (early and mid 1990s) and developed a predictive model of mortality. A nested case-control was done. All 251 patients over 14 years old with positive blood cultures for S. aureus were selected. MRSA (methicillin resistant S. aureus) was isolated in 63% of the cases. When comparing the two periods MRSA community-acquired bacteremia increased from 4% to 16% (p=0.01). There was no significant difference in the mortality rate between the two periods (39% and 33%, p=0.40). Intravascular catheters provoked 24% of the cases of bacteremia and were associated with the lowest rate of mortality. In a logistic regression analysis, three variables were associated with death: septic shock, source of bacteraemia and resistance to methicillin. The probability of dying among patients with MRSA and those with methicillin sensitive S. aureus bacteraemia ranged from 10% to 90% and from 4% to 76%, respectively, depending on the source of the bacteraemia and the occurrence of septic shock. The MRSA found in Brazil may be a particularly virulent strain.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702002000600004
Editor: | Brazilian Society of Infectious Diseases
Relação: | 10.1590/S1413-86702002000600004
Formato: | text/html
Fonte: | Brazilian Journal of Infectious Diseases  v.6 n.6 2002
Fonte: | info:eu-repo/semantics/openAccess