Data/hora: 01/06/2024 16:31:43

Provedor de dados: | Brazilian Journal of Infectious Diseases
País: | Brazil
Título: | A survey on pulmonary pathogens and their antibiotic susceptibility among cystic fibrosis patients
Autores: | Khanbabaee,Ghamartaj; Akbarizadeh,Majidreza; Sayyari,Aliakbar; Ashayeri-Panah,Mitra; Abdollahgorji,Fatemeh; Sheibani,Kourosh; Rezaeig,Nima.
Data: | 2012-04-01
Ano: | 2012
Palavras-chave: | Cystic fibrosis; Respiratory tract; Infections; Products with antimicrobial action.
Resumo: | OBJECTIVE:This study was performed to investigate frequency and antimicrobial susceptibility of pulmonary pathogens in cystic fibrosis (CF) patients. METHODS: 129 pediatric patients with CF were enrolled in this cross-sectional study. Microbiological cultures were performed based on sputum or pharyngeal swabs. Antibiotic susceptibilities of the isolated bacteria were determined by the disk diffusion method. RESULTS: The main infecting pathogens were Pseudomonas aeruginosa (38.8%), Klebsiella pneumoniae (11.6%) and Staphyloccus areus (9.3%), respectively. The most active antibiotics included rifampin (91.7% susceptibility), vancomycin (85%) and imipenem (83.5%). Emerging resistance against aminoglycosides was observed. CONCLUSION: Regarding in vitro susceptibility results, cyclic treatment of long-term oral azithromycin and inhaled tobramycin could prophylactically be applied, and during exacerbations, imipenem or ceftazidime in combination with an aminoglycoside such as amikacin could be considered the drugs of choice.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000200003
Editor: | Brazilian Society of Infectious Diseases
Relação: | 10.1590/S1413-86702012000200003
Formato: | text/html
Fonte: | Brazilian Journal of Infectious Diseases  v.16 n.2 2012
Fonte: | info:eu-repo/semantics/openAccess