Data/hora: 02/06/2024 12:49:40

Provedor de dados: | Brazilian Journal of Infectious Diseases
País: | Brazil
Título: | The incidence of cytomegalovirus infection in lung transplant recipients under universal prophylaxis with intravenous ganciclovir
Autores: | Schröeder,Regina; Michelon,Tatiana; Wurdig,João; Fagundes,Iara; Schio,Sadi; Sanchez,Leticia; Camargo,José J.; Sukkienik,Teresa C.; Pasqualotto,Alessandro C.; Neumann,Jorge.
Data: | 2007-04-01
Ano: | 2007
Palavras-chave: | Cytomegalovirus; Antigenemia; Lung transplantation; Ganciclovir; Prophylaxis.
Resumo: | The best strategy for control of cytomegalovirus (CMV) infection in lung transplant patients is still not determined. The aim of this study was to document the incidence of CMV infection in a cohort of lung transplant recipients under universal prophylaxis with intravenous ganciclovir. All patients received immunosuppressive regimens consisting of cyclosporine, azathioprine, and prednisone. Regardless of CMV serostatus, intravenous ganciclovir was prescribed for every patient in the first 3 months post-transplantation. CMV infection was defined as the detection of CMV pp65 in leukocytes. Eighty-two lung transplant patients were included over a 5-year period. The incidence of CMV infection in the first year post-transplantation was 68.3%, occurring after a median length of 114 days (range, 26-343 days). This study revealed a high incidence of CMV infection in the first year following lung transplantation despite prolonged universal ganciclovir prophylaxis.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000200008
Editor: | Brazilian Society of Infectious Diseases
Relação: | 10.1590/S1413-86702007000200008
Formato: | text/html
Fonte: | Brazilian Journal of Infectious Diseases  v.11 n.2 2007
Fonte: | info:eu-repo/semantics/openAccess