Data/hora: 02/06/2024 14:08:51

Provedor de dados: | 55
País: | Brazil
Título: | To evaluate of the effect of adding licorice to the standard treatment regimen of Helicobacter pylori
Autores: | Hajiaghamohammadi,Ali Akbar; Zargar,Ali; Oveisi,Sonia; Samimi,Rasoul; Reisian,Sedigheh.
Data: | 2016-12-01
Ano: | 2016
Palavras-chave: | Helicobacter pylori; Licorice; Dyspepsia; Peptic ulcer.
Resumo: | ABSTRACT  Objective: The aim of this study was to evaluate the effect of licorice in H. pylori eradication in patients suffering from dyspepsia either with peptic ulcer disease (PUD) or non-ulcer dyspepsia (NUD) in comparison to the clarithromycin-based standard triple regimen.  Methods: In this randomized controlled clinical trial, 120 patients who had positive rapid urease test were included and assigned to two treatment groups: control group that received a clarithromycin-based triple regimen, and study group that received licorice in addition to the clarithromycin-based regimen for two weeks. H. pylori eradication was assessed six weeks after therapy. Data was analyzed by chi-square and t-test with SPSS 16 software.  Results: Mean ages and SD were 38.8 ± 10.9 and 40.1 ± 10.4 for the study and control groups, respectively, statistically similar. Peptic ulcer was found in 30% of both groups. Response to treatment was 83.3% and 62.5% in the study and control groups, respectively. This difference was statistically significant.  Conclusion: Addition of licorice to the triple clarithromycin-based regimen increases H. pylori eradication, especially in the presence of peptic ulcer disease.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000600534
Editor: | Brazilian Society of Infectious Diseases
Relação: | 10.1016/j.bjid.2016.07.015
Formato: | text/html
Fonte: | Brazilian Journal of Infectious Diseases  v.20 n.6 2016
Fonte: | info:eu-repo/semantics/openAccess