Data/hora: 11/06/2024 04:13:51

Provedor de dados: | 56
País: | Brazil
Título: | Histologic distribution of insulin and glucagon receptors
Autores: | Watanabe,M.; Hayasaki,H.; Tamayama,T.; Shimada,M.
Data: | 1998-02-01
Ano: | 1998
Palavras-chave: | Radioautography; Insulin; Glucagon; Receptor; Distribution.
Resumo: | Insulin and glucagon are the hormonal polypeptides secreted by the B and A cells of the endocrine pancreas, respectively. Their major physiologic effects are regulation of carbohydrate metabolism, but they have opposite effects. Insulin and glucagon have various physiologic roles, in addition to the regulation of carbohydrate metabolism. The physiologic effects of insulin and glucagon on the cell are initiated by the binding of each hormone to receptors on the target cells. Morphologic studies may be useful for relating biochemical, physiologic, and pharmacologic information on the receptors to an anatomic background. Receptor radioautography techniques using radioligands to label specific insulin and glucagon receptors have been successfully applied to many tissues and organs. In this review, current knowledge of the histologic distribution of insulin and glucagon receptors is presented with a brief description of receptor radioautography techniques
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000200008
Editor: | Associação Brasileira de Divulgação Científica
Relação: | 10.1590/S0100-879X1998000200008
Formato: | text/html
Fonte: | Brazilian Journal of Medical and Biological Research  v.31 n.2 1998
Fonte: | info:eu-repo/semantics/openAccess