Data/hora: 03/06/2024 04:46:53

Provedor de dados: | Brazilian Journal of Medical and Biological Research
País: | Brazil
Título: | Long-term efficacy of a rural community-based integrated intervention for prevention and management of chronic obstructive pulmonary disease: a cluster randomized controlled trial in China's rural areas
Autores: | Yuan,X.; Tao,Y.; Zhao,J.P.; Liu,X.S.; Xiong,W.N.; Xie,J.G.; Ni,W.; Xu,Y.J.; Liu,H.G.
Data: | 2015-11-01
Ano: | 2015
Palavras-chave: | Chronic obstructive pulmonary disease; Randomized controlled trial; Integrated intervention; Rural area; Lung function; Smoking cessation.
Resumo: | This study aimed to assess the efficacy of a rural community-based integrated intervention for early prevention and management of chronic obstructive pulmonary disease (COPD) in China. This 18-year cluster-randomized controlled trial encompassing 15 villages included 1008 patients (454 men and 40 women in the intervention group [mean age, 54 ± 10 years]; 482 men and 32 women in the control group [mean age, 53 ± 10 years]) with confirmed COPD or at risk for COPD. Villages were randomly assigned to the intervention or the control group, and study participants residing within the villages received treatment accordingly. Intervention group patients took part in a program that included systematic health education, smoking cessation counseling, and education on management of COPD. Control group patients received usual care. The groups were compared after 18 years regarding the incidence of COPD, decline in lung function, and mortality of COPD. COPD incidence was lower in the intervention group than in the control group (10% vs 16%, &lt;0.05). A decline in lung function was also significantly delayed in the intervention group compared to the control group of COPD and high-risk patients. The intervention group showed significant improvement in smoking cessation compared with the control group, and smokers in the intervention group had lower smoking indices than in the control group (350 vs 450, &lt;0.05). The intervention group also had a significantly lower cumulative COPD-related death rate than the control group (37% vs 47%, &lt;0.05). A rural community-based integrated intervention is effective in reducing the incidence of COPD among those at risk, delaying a decline in lung function in COPD patients and those at risk, and reducing mortality of COPD.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015001101023
Editor: | Associação Brasileira de Divulgação Científica
Relação: | 10.1590/1414-431x20154385
Formato: | text/html
Fonte: | Brazilian Journal of Medical and Biological Research  v.48 n.11 2015
Fonte: | info:eu-repo/semantics/openAccess