Data/hora: 03/06/2024 02:55:45

Provedor de dados: | Brazilian Journal of Medical and Biological Research
País: | Brazil
Título: | Hospital strain colonization by Staphylococcus epidermidis
Autores: | Blum-Menezes,D.; Bratfich,O.J.; Padoveze,M.C.; Moretti,M.L.
Data: | 2009-03-01
Ano: | 2009
Palavras-chave: | Staphylococcus epidermidis; Microbiota; Biofilm; Central venous catheter.
Resumo: | The skin and mucous membranes of healthy subjects are colonized by strains of Staphylococcus epidermidis showing a high diversity of genomic DNA polymorphisms. Prolonged hospitalization and the use of invasive procedures promote changes in the microbiota with subsequent colonization by hospital strains. We report here a patient with prolonged hospitalization due to chronic pancreatitis who was treated with multiple antibiotics, invasive procedures and abdominal surgery. We studied the dynamics of skin colonization by S. epidermidis leading to the development of catheter-related infections and compared the genotypic profile of clinical and microbiota strains by pulsed field gel electrophoresis. During hospitalization, the normal S. epidermidis skin microbiota exhibiting a polymorphic genomic DNA profile was replaced with a hospital-acquired biofilm-producer S. epidermidis strain that subsequently caused repetitive catheter-related infections.
Tipo: | Info:eu-repo/semantics/other
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000300011
Editor: | Associação Brasileira de Divulgação Científica
Relação: | 10.1590/S0100-879X2009000300011
Formato: | text/html
Fonte: | Brazilian Journal of Medical and Biological Research  v.42 n.3 2009
Fonte: | info:eu-repo/semantics/openAccess