Data/hora: 02/06/2024 13:18:27

Provedor de dados: | Brazilian Journal of Medical and Biological Research
País: | Brazil
Título: | Alternative mitochondrial functions in cell physiopathology: beyond ATP production
Autores: | Kowaltowski,A.J.
Data: | 2000-02-01
Ano: | 2000
Palavras-chave: | Mitochondrial permeability transition; Uncoupling proteins; Alternative oxidase; Cardioprotection; Free radicals; Aging.
Resumo: | It is well known that mitochondria are the main site for ATP generation within most tissues. However, mitochondria also participate in a surprising number of alternative activities, including intracellular Ca2+ regulation, thermogenesis and the control of apoptosis. In addition, mitochondria are the main cellular generators of reactive oxygen species, and may trigger necrotic cell death under conditions of oxidative stress. This review concentrates on these alternative mitochondrial functions, and their role in cell physiopathology.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000200014
Editor: | Associação Brasileira de Divulgação Científica
Relação: | 10.1590/S0100-879X2000000200014
Formato: | text/html
Fonte: | Brazilian Journal of Medical and Biological Research  v.33 n.2 2000
Fonte: | info:eu-repo/semantics/openAccess