Data/hora: 11/06/2024 11:03:38

Provedor de dados: | 56
País: | Brazil
Título: | What ethologically based models have taught us about the neural systems underlying fear and anxiety
Autores: | Canteras,N.S.; Mota-Ortiz,S.R.; Motta,S.C.
Data: | 2012-04-01
Ano: | 2012
Palavras-chave: | Fear; Predator exposure; Social threat; Fear memory; Contextual fear; Hypothalamus.
Resumo: | Classical Pavlovian fear conditioning to painful stimuli has provided the generally accepted view of a core system centered in the central amygdala to organize fear responses. Ethologically based models using other sources of threat likely to be expected in a natural environment, such as predators or aggressive dominant conspecifics, have challenged this concept of a unitary core circuit for fear processing. We discuss here what the ethologically based models have told us about the neural systems organizing fear responses. We explored the concept that parallel paths process different classes of threats, and that these different paths influence distinct regions in the periaqueductal gray - a critical element for the organization of all kinds of fear responses. Despite this parallel processing of different kinds of threats, we have discussed an interesting emerging view that common cortical-hippocampal-amygdalar paths seem to be engaged in fear conditioning to painful stimuli, to predators and, perhaps, to aggressive dominant conspecifics as well. Overall, the aim of this review is to bring into focus a more global and comprehensive view of the systems organizing fear responses.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000400006
Editor: | Associação Brasileira de Divulgação Científica
Relação: | 10.1590/S0100-879X2012007500042
Formato: | text/html
Fonte: | Brazilian Journal of Medical and Biological Research  v.45 n.4 2012
Fonte: | info:eu-repo/semantics/openAccess