Data/hora: 13/06/2024 07:55:54

Provedor de dados: | 56
País: | Brazil
Título: | Obese women on a low energy rice and bean diet: effects of leucine, arginine or glycine supplementation on protein turnover
Autores: | Marchini,J.S.; Lambertini,C.R.; Ferriolli,E.; Dutra de Oliveira,J.E.
Data: | 2001-10-01
Ano: | 2001
Palavras-chave: | Obese women; Protein; Glycine; Arginine; Leucine; Stable isotope.
Resumo: | This study examined if leucine, arginine or glycine supplementation in adult obese patients (body mass index of 33 ± 4 kg/m²) consuming a Brazilian low energy and protein diet (4.2 MJ/day and 0.6 g protein/kg) affects protein and amino acid metabolism. After four weeks adaptation to this diet, each subject received supplements of these amino acids (equivalent to 0.2 g protein kg-1 day-1) in random order. On the seventh day of each amino acid supplementation, a single-dose 15N-glycine study was carried out. There were no significant differences in protein flux, synthesis or breakdown. The protein flux (grams of nitrogen, gN/9 h) was 55 ± 24 during the nonsupplemented diet intake and 39 ± 10, 44 ± 22 and 58 ± 35 during the leucine-, glycine- and arginine-supplemented diet intake, respectively; protein synthesis (gN/9 h) was 57 ± 24, 36 ± 10, 41 ± 22 and 56 ± 36, respectively; protein breakdown (gN/9 h) was 51 ± 24, 34 ± 10, 32 ± 28 and 53 ± 35, respectively; kinetic balance (gN/9 h) was 3.2 ± 1.8, 4.1 ± 1.7, 3.4 ± 2.9 and 3.9 ± 1.6. There was no difference in amino acid profiles due to leucine, arginine or glycine supplementation. The present results suggest that 0.6 g/kg of dietary protein is enough to maintain protein turnover in obese women consuming a reduced energy diet and that leucine, arginine or glycine supplementation does not change kinetic balance or protein synthesis.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001001000007
Editor: | Associação Brasileira de Divulgação Científica
Relação: | 10.1590/S0100-879X2001001000007
Formato: | text/html
Fonte: | Brazilian Journal of Medical and Biological Research  v.34 n.10 2001
Fonte: | info:eu-repo/semantics/openAccess