Data/hora: 03/06/2024 03:48:38

Provedor de dados: | Brazilian Journal of Medical and Biological Research
País: | Brazil
Título: | Pathogenesis of Salmonella-induced enteritis
Autores: | Santos,R.L.; Tsolis,R.M.; Bäumler,A.J.; Adams,L.G.
Data: | 2003-01-01
Ano: | 2003
Palavras-chave: | Salmonella typhimurium; Enteritis; Diarrhea; Salmonellosis.
Resumo: | Infections with Salmonella serotypes are a major cause of food-borne diseases worldwide. Animal models other than the mouse have been employed for the study of nontyphoidal Salmonella infections because the murine model is not suitable for the study of Salmonella-induced diarrhea. The microbe has developed mechanisms to exploit the host cell machinery to its own purpose. Bacterial proteins delivered directly into the host cell cytosol cause cytoskeletal changes and interfere with host cell signaling pathways, which ultimately enhance disease manifestation. Recently, marked advances have been made in our understanding of the molecular interactions between Salmonella serotypes and their hosts. Here, we discuss the molecular basis of the pathogenesis of Salmonella-induced enteritis.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000100002
Editor: | Associação Brasileira de Divulgação Científica
Relação: | 10.1590/S0100-879X2003000100002
Formato: | text/html
Fonte: | Brazilian Journal of Medical and Biological Research  v.36 n.1 2003
Fonte: | info:eu-repo/semantics/openAccess