Data/hora: 11/06/2024 01:25:50

Provedor de dados: | Brazilian Journal of Medical and Biological Research
País: | Brazil
Título: | Effects of high- and moderate-intensity exercise on central hemodynamic and oxygen uptake recovery kinetics in CHF-COPD overlap
Autores: | Mazzuco,A.; Souza,A.S.; Medeiros,W.M.; Sperandio,P.A.; Alencar,M.C.N.; Arbex,F.F.; Neder,J.A.; Borghi-Silva,A.
Data: | 2020-01-01
Ano: | 2020
Palavras-chave: | Chronic heart failure; Chronic obstructive pulmonary disease; Oxygen uptake; Heart rate; Recovery kinetics; Exercise test.
Resumo: | The oxygen uptake (V˙O2) kinetics during onset of and recovery from exercise have been shown to provide valuable parameters regarding functional capacity of both chronic obstructive pulmonary disease (COPD) and chronic heart failure (CHF) patients. To investigate the influence of comorbidity of COPD in patients with CHF with reduced ejection fraction on recovery from submaximal exercise, 9 CHF-COPD male patients and 10 age-, gender-, and left ventricle ejection fraction (LVEF)-matched CHF patients underwent constant-load exercise tests (CLET) at moderate and high loads. The V˙O2, heart rate (HR), and cardiac output (CO) recovery kinetics were determined for the monoexponential relationship between these variables and time. Within-group analysis showed that the recovery time constant of HR (P&lt;0.05, d=1.19 for CHF and 0.85 for CHF-COPD) and CO (P&lt;0.05, d=1.68 for CHF and 0.69 for CHF-COPD) and the mean response time (MRT) of CO (P&lt;0.05, d=1.84 for CHF and 0.73 for CHF-COPD) were slower when moderate and high loads were compared. CHF-COPD patients showed smaller amplitude of CO recovery kinetics (P&lt;0.05) for both moderate (d=2.15) and high (d=1.07) CLET. Although the recovery time constant and MRT means were greater in CHF-COPD, CHF and CHF-COPD groups were not differently affected by load (P&gt;0.05 in group vs load analysis). The ventilatory efficiency was related to MRT of V˙O2 during high CLET (r=0.71). Our results suggested that the combination of CHF and COPD may further impair the recovery kinetics compared to CHF alone.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2020000300602
Editor: | Associação Brasileira de Divulgação Científica
Relação: | 10.1590/1414-431x20199391
Formato: | text/html
Fonte: | Brazilian Journal of Medical and Biological Research  v.53 n.3 2020
Fonte: | info:eu-repo/semantics/openAccess