Data/hora: 02/06/2024 11:49:45

Provedor de dados: | Brazilian Journal of Microbiology
País: | Brazil
Título: | Heterogenic colonization patterns by Leptospira interrogans in Rattus norvegicus from urban slums
Autores: | Santos,Ana Amélia Nunes; Figueira,Cláudio Pereira; Reis,Mitermayer Galvão dos; Costa,Federico; Ristow,Paula.
Data: | 2015-12-01
Ano: | 2015
Palavras-chave: | Leptospira interrogans; Renal colonization; Natural reservoirs; Rattus norvegicus.
Resumo: | Abstract We evaluated the renal colonization by Leptospira interrogans in Rattus norvegicus (rats), as it is the major natural reservoir of urban leptospirosis. We caught 72 R. norvegicus, out of which 32 were found to be positive for L. interrogans by immunofluorescence assay. From these rats, we selected 17 and divided them into six groups based on the mass-age/sex. We performed the immunohistochemistry test against L. interrogans in the kidney sections of the rats and systematically counted the colonized tubules (CTs) in 20 fields. The proportion of positive fields varied from 5% to 95%. The number of CTs in 20 fields varied from 0.5 to 85.5. These differences were not related to age or sex of the animals. The characterization of leptospiral colonization patterns in the natural reservoirs is important to better understand the host-pathogen interactions in leptospirosis.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822015000401161
Editor: | Sociedade Brasileira de Microbiologia
Relação: | 10.1590/S1517-838246420140873
Formato: | text/html
Fonte: | Brazilian Journal of Microbiology  v.46 n.4 2015
Fonte: | info:eu-repo/semantics/openAccess