Data/hora: 18/06/2024 10:11:01

Provedor de dados: | 58
País: | Brazil
Título: | Anti dermatophytic therapy: prospects for the discovery of new drugs from natural products
Autores: | Soares,Luciana Arantes; Sardi,Janaína de Cássia Orlandi; Gullo,Fernanda Patrícia; Pitangui,Nayla de Souza; Scorzoni,Liliana; Leite,Fernanda Sangalli; Giannini,Maria José Soares Mendes; Almeida,Ana Marisa Fusco.
Data: | 2013-12-01
Ano: | 2013
Palavras-chave: | Dermatophytes; Filamentous fungi; Natural products; Synthetic product.
Resumo: | Millions of people and animals suffer from superficial infections caused by a group of highly specialized filamentous fungi, the dermatophytes, which only infect keratinized structures. With the appearance of AIDS, the incidence of dermatophytosis has increased. Current drug therapy used for these infections is often toxic, long-term, and expensive and has limited effectiveness; therefore, the discovery of new anti dermatophytic compounds is a necessity. Natural products have been the most productive source for new drug development. This paper provides a brief review of the current literature regarding the presence of dermatophytes in immunocompromised patients, drug resistance to conventional treatments and new anti dermatophytic treatments.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822013000400003
Editor: | Sociedade Brasileira de Microbiologia
Relação: | 10.1590/S1517-83822014005000011
Formato: | text/html
Fonte: | Brazilian Journal of Microbiology  v.44 n.4 2013
Fonte: | info:eu-repo/semantics/openAccess