Data/hora: 01/06/2024 19:05:49

Provedor de dados: 	Brazilian Journal of Microbiology	
País: 	Brazil	
Título: 	Epidemiology of diabetic foot infections in a reference tertiary hospital in India	
Autores: 	Saseedharan,Sanjith; Sahu,Manisa; Chaddha,Roonam; Pathrose,Edwin; Bal,Arun; Bhalekar,Pallavi; Sekar,Priyadharshini; Krishnan,Padma.	
Data: 	2018-06-01	
Ano: 	2018	
Palavras-chave: 	Diabetic foot infection; BlaNDM; MRSA.	
Resumo: 	Abstract  Introduction The present study attempts to examine the microbial profile and antibiotic susceptibility of diabetic foot infections in the intensive care unit of a tertiary referral centre for diabetic foot. As part of the study, we also attempted to find the prevalence of blaNDM-like gene among carbapenem-resistant gram negative infections.  Methodology A prospective study of 261 patients with diabetic foot infections was performed during the period between January 2014 and June 2014.  Results A total of 289 isolates were obtained from 178 tissue samples from 261 patients, 156 (59.7%) males and 105 (40.2%) females, with a mean age of 58 years (-15 years), having diabetic foot infection. No growth was seen in thirty eight (17.6%) tissue samples. Out of the total samples, 44.3% were monomicrobial and 55.7% were polymicrobial. Gram negative pathogens were predominant (58.5%). Seven of the total isolates were fungal; 0.7% showed pure fungal growth and 1.7% were mixed, grown along with some bacteria. The most frequently isolated bacteria were Staphylococcus aureus (26.9%), followed by Pseudomonas aeruginosa (20.9%). Of the 58.5% gram negative pathogens, 16.5% were Enterobacteriaceae resistant to carbapenems. Among these isolates, 4 (25%) were positive for blaNDM-like gene. Among the rest, 18.6% were carbapenem-resistant Pseudomonas, among which 4 (36.3%) were blaNDM. Among the Staphylococci, 23.7% were methicillin-resistant Staphylococcus aureus.  Conclusions Our results support the recent view that gram negative organisms, depending on the geographical location, may be predominant in DFIs. There is an increase in multidrug-resistant pathogens, especially carbapenem resistance and this is creeping rapidly. We need to be more judicious while using empiric antibiotics.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822018000200401	
Editor: 	Sociedade Brasileira de Microbiologia	
Relação: 	10.1016/j.bjm.2017.09.003	
Formato: 	text/html	
Fonte: 	Brazilian Journal of Microbiology  v.49 n.2 2018	
Fonte: 	info:eu-repo/semantics/openAccess