Data/hora: 13/06/2024 23:25:39

Provedor de dados: | 58
País: | Brazil
Título: | Antimicrobial activity of some medicinal plants from the cerrado of the central-western region of Brazil
Autores: | Violante,Ivana Maria Póvoa; Hamerski,Lidilhone; Garcez,Walmir Silva; Batista,Ana Lucia; Chang,Marilene Rodrigues; Pott,Vali Joana; Garcez,Fernanda Rodrigues.
Data: | 2012-12-01
Ano: | 2012
Palavras-chave: | Antifungal; Antibacterial; Antimicrobial; Artemia salina; Cerrado.
Resumo: | Ethanol extracts from six selected species from the Cerrado of the Central-Western region of Brazil, which are used in traditional medicine for the treatment of infectious diseases and other medical conditions, namely Erythroxylum suberosum St. Hil. (Erythroxylaceae), Hyptis crenata Pohl. ex Benth. (Lamiaceae), Roupala brasiliensis Klotz. (Proteaceae), Simarouba versicolor St. Hil. (Simaroubaceae), Guazuma ulmifolia Lam. (Sterculiaceae) and Protium heptaphyllum (Aubl.) March. (Burseraceae), as well as fractions resulting from partition of these crude extracts, were screened in vitro for their antifungal and antibacterial properties. The antimicrobial activities were assessed by the broth microdilution assay against six control fungal strains, Candida albicans, C. glabrata, C. krusei, C. parapsilosis, C. tropicalis and Cryptococcus neoformans, and five control Gram-positive and negative bacterial strains, Escherichia coli, Enterococcus faecalis, Klebsiella pneumoniae, Pseudomonas aeruginosa and Staphylococcus aureus. Toxicity of the extracts and fractions against Artemia salina was also evaluated in this work. All plants investigated showed antimicrobial properties against at least one microorganism and two species were also significantly toxic to brine shrimp larvae. The results tend to support the traditional use of these plants for the treatment of respiratory and gastrointestinal disorders and/or skin diseases, opening the possibility of finding new antimicrobial agents from these natural sources.Among the species investigated, Hyptis crenata, Erythroxylum suberosum and Roupala brasiliensis were considered the most promising candidates for developing of future bioactivity-guided phytochemical investigations.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822012000400009
Editor: | Sociedade Brasileira de Microbiologia
Relação: | 10.1590/S1517-83822012000400009
Formato: | text/html
Fonte: | Brazilian Journal of Microbiology  v.43 n.4 2012
Fonte: | info:eu-repo/semantics/openAccess