Data/hora: 11/06/2024 12:18:08

Provedor de dados: | Brazilian Journal of Microbiology
País: | Brazil
Título: | In vitro susceptibility to methicillin, vancomycin and linezolid of staphylococci isolated from bloodstream infections in eastern Turkey
Autores: | Tekin,Alicem; Dal,Tuba; Deveci,Özcan; Tekin,Recep; Özcan,Nida; Atmaca,Selahattin; Dayan,Saim.
Data: | 2014-09-01
Ano: | 2014
Palavras-chave: | Staphylococcus; Methicillin; Linezolid; Vancomycin.
Resumo: | Staphylococcus species are one of the major causes of bacterial bloodstream infections. Multi-resistant staphylococci infections are major therapeutic problems. This study was aimed to detect methicillin, linezolid and vancomycin susceptibilities of Staphylococcus isolates. A total of 870 Staphylococcus strains isolated from blood cultures of hospitalized patients with BSI. Antimicrobial susceptibilities of methicillin, linezolid and vancomycin were detected according to the Clinical and Laboratory Standards Institute (CLSI). A total of 771 (88.6%) isolates were coagulase-negative staphylococci (CoNS). 700 (80.5%) isolates were methicillin-resistant (MR) and 170 (19.5%) were methicillin-susceptible (MS). All the MS isolates were also susceptible to linezolid. However 15 (1.7%) of MR strains were resistant to linezolid. The minimum inhibitory concentration range for the linezolid-resistant isolates by Etest was 6-32 µg/mL. The difference between linezolid susceptibilities for MS and MR staphylococci was not quite statistically significant (p = 0.052). There was no statistically significant difference between S. aureus and CoNS isolates for linezolid susceptibility. All of the isolates were susceptible to vancomycin. In conclusion, linezolid is currently an efficient option for the treatment of methicillin-resistant staphylococci infections.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822014000300010
Editor: | Sociedade Brasileira de Microbiologia
Relação: | 10.1590/S1517-83822014000300010
Formato: | text/html
Fonte: | Brazilian Journal of Microbiology  v.45 n.3 2014
Fonte: | info:eu-repo/semantics/openAccess