Data/hora: 13/06/2024 05:05:27

Provedor de dados: | 58
País: | Brazil
Título: | Influence of probiotics on Candida presence and IgA anti-Candida in the oral cavity
Autores: | Santos,Agda Lima dos; Jorge,Antônio Olavo Cardoso; Santos,Silvana Soléo Ferreira dos; Silva,Célia Regina Gonçalves e; Leão,Mariella Vieira Pereira.
Data: | 2009-12-01
Ano: | 2009
Palavras-chave: | Candida; IgA; Lactobacillus casei; Bifidobacterium.
Resumo: | Probiotics are defined as microorganisms that promote benefits to host health, mainly by regulating resident microbiota. Disequilibrium in microbiota can favor the growth of opportunist microorganisms and the development of pathologies, like candidosis caused by yeasts of the Candida genus. This work evaluated whether probiotics consumption was able to influence a specific immunological response to Candida and the presence of these yeasts in the oral cavity. Saliva samples were collected from healthy individuals and plated in Dextrose Saboraud Agar with chloramphenicol. Individuals presenting Candida in the oral cavity used the probiotic Yakult LBâ for 20 days, after which new collections and identifications were performed. Anti-Candida IgA analysis was conducted using the ELISA technique. Analysis of the results showed a significant reduction in Candida prevalence (46%) and mean Candida CFU/mL counts (65%). The Candida species identified were C. albicans (98%) and C.tropicalis (2%), before and after probiotics consumption. Immunological analysis demonstrated a significant reduction in anti-Candida IgA levels after probiotics use, probably due to less antigenic stimulation. In conclusion, in the individuals studied, probiotics use significantly reduced the amount of Candida in the oral cavity, possibly due to competition between the yeasts rather than by specific secretory immune response stimulation.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822009000400030
Editor: | Sociedade Brasileira de Microbiologia
Relação: | 10.1590/S1517-83822009000400030
Formato: | text/html
Fonte: | Brazilian Journal of Microbiology  v.40 n.4 2009
Fonte: | info:eu-repo/semantics/openAccess