Data/hora: 13/06/2024 10:33:08

Provedor de dados: | 58
País: | Brazil
Título: | Antimicrobial resistance in Enterobacteriaceae in Brazil: focus on β-lactams and polymyxins
Autores: | Sampaio,Jorge Luiz Mello; Gales,Ana Cristina.
Data: | 2016-12-01
Ano: | 2016
Palavras-chave: | ESBL; KPC; NDM; Extended spectrum β-lactamases; New Delhi metallo-β-lactamase; Klebsiella pneumoniae carbapenemase; Polymyxin B; Colistin; Antimicrobial resistance; Carbapenemases; Brazil; Enterobacteriaceae.
Resumo: | ABSTRACT During the last 30 years there has been a dissemination of plasmid-mediated β-lactamases in Enterobacteriaceae in Brazil. Extended spectrum β-lactamases (ESBL) are widely disseminated in the hospital setting and are detected in a lower frequency in the community setting. Cefotaximases are the most frequently detected ESBL type and Klebsiella pneumoniae is the predominant species among ESBL producers. Klebsiella pneumoniae carbapenemase-producing Enterobacteriaceae became widely disseminated in Brazil during the last decade and KPC production is currently the most frequent resistance mechanism (96.2%) in carbapenem resistant K. pneumoniae. To date KPC-2 is the only variant reported in Brazil. Polymyxin B resistance in KPC-2-producing K. pneumoniae has come to an alarming rate of 27.1% in 2015 in São Paulo, the largest city in Brazil. New Delhi metallo-β-lactamase was detected in Brazil in 2013, has been reported in different Brazilian states but are not widely disseminated. Antimicrobial resistance in Enterobacteriaceae in Brazil is a very serious problem that needs urgent actions which includes both more strict adherence to infection control measures and more judicious use of antimicrobials.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822016000500031
Editor: | Sociedade Brasileira de Microbiologia
Relação: | 10.1016/j.bjm.2016.10.002
Formato: | text/html
Fonte: | Brazilian Journal of Microbiology  v.47 suppl.1 2016
Fonte: | info:eu-repo/semantics/openAccess