Data/hora: 02/06/2024 13:26:11

Provedor de dados: | Brazilian Journal of Microbiology
País: | Brazil
Título: | Disinfectant and antibiotic activities: a comparative analysis in Brazilian hospital bacterial isolates
Autores: | Guimarães,Márcia Aparecida; Tibana,Anita; Nunes,Marly Paiva; Santos,Kátia Regina Netto dos.
Data: | 2000-09-01
Ano: | 2000
Palavras-chave: | Disinfectant activity; Antibiotic activity; Hospital isolates.
Resumo: | Nosocomial infections are an important cause of morbidity and mortality all over the world. It has been shown that appropriate environmental hygienic and disinfection practices can be very helpful to hospital infection control. The purpose of this study was to evaluate the bactericidal activity of some disinfectants against antibiotic-susceptible and antibiotic-resistant hospital bacterial isolates. The susceptibility of 27 clinical isolates to disinfectants and antibiotics was determined by the Association of Official Analytical Chemist’s (AOAC) Use-Dilution method and by the Kirby-Bauer method, respectively. All strains tested were susceptible to sodium hypochlorite, glutaraldehyde and to the association quaternary ammonium - formaldehyde - ethyl alcohol disinfectants. However, the susceptibility of strains to phenol and to one quaternary ammonium compound was variable. Among twenty-one antibiotic-multiresistant strains (methicillin-resistant staphylococci, Enterococcus spp, Pseudomonas aeruginosa, Klebsiella pneumoniae, Proteus mirabilis, Enterobacter cloacae, Serratia marcescens and Escherichia coli) eleven (52%) and eight (38%) strains were resistant to the quaternary ammonium and phenol compounds, respectively. Among six isolates that demonstrated susceptibility to antibiotics (staphylococci, Enterococcus spp, P. mirabilis, E. cloacae and E. coli) two strains (33%) showed resistance to these disinfectants. The results demonstrated the lack of correlation between antibiotic-susceptibility and susceptibility to disinfectants in hospital strains.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822000000300008
Editor: | Sociedade Brasileira de Microbiologia
Relação: | 10.1590/S1517-83822000000300008
Formato: | text/html
Fonte: | Brazilian Journal of Microbiology  v.31 n.3 2000
Fonte: | info:eu-repo/semantics/openAccess